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KMID : 0603720100160040260
Journal of Korean Society of Medical Informatics
2010 Volume.16 No. 4 p.260 ~ p.272
Integration and Evaluation of Clinical Decision Support Systems for Diagnosis Idopathics Pulmo-nary Fibrosis (IPF)
Lee Yun-Hee

Chae Young-Moon
Jeon Sung-Wan
Abstract
Objectives: The purpose of this study was to develop clinical decision support systems (CDSS) that are integrated with hospi-tal information systems for the differential diagnosis of idiopathic pulmonary fibrosis (IPF).

Methods: The integrated CDSS were validated and evaluated by physicians. Knowledge modeling for diagnosing IPF was performed by knowledge working groups, composed of radiologists and respiratory specialists. In order to develop the model for CDSS diagnosis, the clinical cases were collected from 290 cases from Seoul National University Hospital and Sevrance Hospital of Yonsei University. For the evaluation of integrated CDSS, interviews were conducted with respiratory specialists and radiologist 2 weeks after ap-plying CDSSs in clinical settings. The CDSS was integrated with the computer vision system (CVS) and diffuse parenchymal lung diseases (DPLD), CDSS developed in our previous project.

Results: Eighteen cases diagnosed as IPF were applied to the collection of diagnostic knowledge and the refined knowledge, the former diagnosed 1 case (6%) and the latter diagnosed 14 cases (78%). Therefore, the refined knowledge performed better than collected knowledge. The validation results of integrat-ed CDSSs showed that 81 cases (74.3%) were diagnosed correctly.

Conclusions: There were 109 cases of IPF diagnosed and initiated on treatment. The significance of this study is in developing integrated CDSS with PACS by acquiring and redefining the knowledge needed for IPF diagnosis. In addition, it is significant for the integration of CDSS to verification and clinical evaluation.
KEYWORD
Clinical Decision Support Systems, Idiopathic Pulmonary Fibrosis, Computer Vision System, Radiology Informa-tion Systems
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